Molybdenum-Catalyzed Sustainable Friedländer Synthesis of Quinolines
نویسندگان
چکیده
منابع مشابه
Metal-free aerobic one-pot synthesis of substituted/annulated quinolines from alcohols via indirect Friedländer annulation.
Metal-free, operationally simple, and highly efficient one-pot aerobic process for the synthesis of functionalized/annulated quinolines is devised from easily available 2-aminobenzyl alcohol/2-aminobenzophenones and alkyl/aryl alcohols for the first time. The process involves two sequential reactions, namely in situ aerial oxidation of alcohols to the corresponding aldehydes/ketones followed by...
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A highly efficient, simple and green solvent-free protocol for the preparation of poly-substituted quinolines via Friedländer hetero-annulation reaction between 2-aminoaryl ketones and carbonyl compounds in the presence of silica-supported P2O5 (P2O5 / SiO2) is described. In this method, the title compounds are obtained in high to exc...
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Quinoline scaffold are found in many natural products and they exhibit remarkable biological activities like Antimalerial, antibacterial, antiasthmatic, antihypertensive, anti-inflammatory agents and antiobesity. Aryl-substituted quinolines act as ligands for 5-lipoxygenase , tyrosine kinase , leukotriene 11 and other receptors. Furthermore, polyquinolines were shown to undergo hierarchical sel...
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ژورنال
عنوان ژورنال: Advanced Synthesis & Catalysis
سال: 2018
ISSN: 1615-4150
DOI: 10.1002/adsc.201800278